The aim of this project is to extend the NMR size limit to large protein complexes by combining recent developments in site-specific labeling schemes with novel NMR methods employing state-of-the-art spectrometers. This will facilitate the study of functionally essential but so far uncharacterized dynamics and substrate interactions of two large protein complexes, providing unprecedented insight into the relationship between dynamics, structure and function.
Datum | 1. 9. 2020 - 31. 8. 2022 |
Země | DE |
Organizace | Univerzita Regensburg |
V rámci projektu | Biofyzika 1, Remco Sprangers Lab |
Rámec a program financování | MSCA-IF-EF-ST - Standard EF |