We aim at clarifying the molecular reaction mechanism in the confines of interfacial water layers and proteinaceous cavities with emphasis on arrangement and mobility of proton relay moieties. Achieving this requires an interdisciplinary, multi-level approach comprising cutting edge technologies like second harmonic imaging, single molecule and time resolved fluorescence microscopy and spectroscopy, advanced calculations of proton transfer, bioengineering of membrane channel and transporter containing systems, synthetic design of biomimetic proton channels, solving protein structures and rational drug design.
Datum | 1. 9. 2019 - 31. 8. 2023 |
Země | AT |
Organizace | Univerzita Johannese Keplera Linec |
V rámci projektu | Institut biofyziky |
Odkaz | www.jku.at |
Rámec a program financování | H2020, MSCA-ITN-2019 - Inovativní testovací sítě |